Valsartan belongs to a group of drugs known as angiotensin receptor blockers (ARBs) and is similar to losartan (Cozaar). Valsartan blocks the ability of angiotensin II to constrict or squeeze arteries and veins, thereby reducing blood pressure and reducing the pressure in the arteries that the heart must pump against.
Valsartan is used to treat high blood pressure. It may be used by itself or in combination with other agents. It has a lesser effect in black patients, similar to ACE inhibitors such as captopril(Capoten), enalapril (Vasotec), benazepril (Lotensin), and lisinopril (Zestril). Valsartan is being studied for use in patients with congestive heart failure. There has been a single case reported of a patient who developed lithium toxicity after adding losartan (Cozaar) to his lithium treatment. The mechanism of the interaction is not known but it is possible that Valsartan shares this interaction. Valsartan should not be used during pregnancy and should be avoided by nursing mothers. Its safety and efficiency in children have not been established.
Valsartan Side effects
Valsartan is generally well-tolerated as a blood pressure medication and side effects are rare. The most common reasons for discontinuation of Valsartan are headache and dizziness.
If a Valsartan overdose is suspected, contact your local poison control centre or emergency room immediately.
Valsartan Usage guidelines
The usual dose in patients with hypertension is 80 mg once daily, but doses of up to 320 mg daily have been prescribed. In patients with congestive heart failure twice daily dosing has been used. Administration with food decreases the absorption of Valsartan by about 40%, so it should be taken on an empty stomach. Capsules should be stored at room temperature, 15-30°C (59-86°F).
In some countries VALSARTAN may also be known as: Alpertan, Sarval, Simultan, Angiosan, Diovane, Tareg, Valaplex, Vartalan, Sarton, Nisis, Cordinate, Provas, Kalpress, Miten, Vals, Alsart